Head to head

Focusrite Scarlett 4i4 4th Gen vs PreSonus Studio 24c

A side-by-side look at Focusrite Scarlett 4i4 4th Gen and PreSonus Studio 24c for podcasters: pricing, features, and where each one wins.

Focusrite Scarlett 4i4 4th Gen

Four inputs, MIDI I/O, and the Scarlett preamp you already trust

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PreSonus Studio 24c

USB-C upgrade over the AudioBox with 192 kHz and cleaner preamps

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At a glance

Focusrite Scarlett 4i4 4th GenPreSonus Studio 24c
Starting priceSee siteSee site
Free planNoNo
Free trialNoNo
Best forProducers or podcasters who need two clean mic preamps, room for outboard gear, and MIDI connectivity in one boxPodcasters and producers who want PreSonus preamp quality, MIDI, and a future-proof USB-C connection in one compact unit

Key features

Focusrite Scarlett 4i4 4th Gen

  • 2 XLR/TRS combo inputs with independent 48V phantom power
  • 2 additional 1/4" TRS line inputs (rear)
  • 4 balanced TRS outputs
  • MIDI In/Out (5-pin DIN)
  • USB-C, 24-bit / 192 kHz, 120 dB dynamic range
  • Up to 69 dB of mic preamp gain

PreSonus Studio 24c

  • USB-C bus powered
  • MIDI In/Out (5-pin DIN)
  • 2 XMAX-L combo XLR/TRS inputs with 48V phantom power
  • 24-bit / 192 kHz converters, 115 dB dynamic range
  • Independent headphone output with volume control
  • Bundles Studio One Artist and Studio Magic plugin suite

Pros and cons

Focusrite Scarlett 4i4 4th Gen

Pros

  • Two clean preamps handle dual-mic podcast setups
  • Four balanced outputs for flexible monitoring routing
  • MIDI I/O included - less common at this price
  • Independent 48V per channel (mix condensers and dynamics freely)

Cons

  • Only one headphone output
  • Larger footprint than the 2i2 - takes more desk space
  • Line inputs are rear-panel only - not ideal for live instrument switching

PreSonus Studio 24c

Pros

  • USB-C native - works with modern laptops without adapters
  • XMAX-L preamps are clean and transparent
  • MIDI I/O included
  • Strong software bundle for the price

Cons

  • Two inputs only - same limit as AudioBox
  • Plastic chassis is less durable than the AudioBox steel body
  • Less brand recognition than Focusrite at the same price

The verdict

Choose Focusrite Scarlett 4i4 4th Gen if

Producers or podcasters who need two clean mic preamps, room for outboard gear, and MIDI connectivity in one box.

The 4i4 is where the Scarlett line starts making sense for more complex setups. Two XLR preamps handle a host and a guest simultaneously, the four balanced outputs let you route to two separate monitor pairs or an external headphone…

Read the full Focusrite Scarlett 4i4 4th Gen review →

Choose PreSonus Studio 24c if

Podcasters and producers who want PreSonus preamp quality, MIDI, and a future-proof USB-C connection in one compact unit.

The Studio 24c is the answer to everyone who asked PreSonus to put a USB-C port on the AudioBox. The XMAX-L preamps are quieter and more transparent than the older design, 192 kHz conversion is now standard, and the 115…

Read the full PreSonus Studio 24c review →

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