Head to head

Focusrite Scarlett 4i4 4th Gen vs PreSonus AudioBox USB 96

A side-by-side look at Focusrite Scarlett 4i4 4th Gen and PreSonus AudioBox USB 96 for podcasters: pricing, features, and where each one wins.

Focusrite Scarlett 4i4 4th Gen

Four inputs, MIDI I/O, and the Scarlett preamp you already trust

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PreSonus AudioBox USB 96

The workhorse 2-input interface that refuses to die

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At a glance

Focusrite Scarlett 4i4 4th GenPreSonus AudioBox USB 96
Starting priceSee siteSee site
Free planNoNo
Free trialNoNo
Best forProducers or podcasters who need two clean mic preamps, room for outboard gear, and MIDI connectivity in one boxBeginners or mobile podcasters who want a durable, no-fuss two-input interface with MIDI and a solid DAW bundle

Key features

Focusrite Scarlett 4i4 4th Gen

  • 2 XLR/TRS combo inputs with independent 48V phantom power
  • 2 additional 1/4" TRS line inputs (rear)
  • 4 balanced TRS outputs
  • MIDI In/Out (5-pin DIN)
  • USB-C, 24-bit / 192 kHz, 120 dB dynamic range
  • Up to 69 dB of mic preamp gain

PreSonus AudioBox USB 96

  • MIDI In/Out (5-pin DIN)
  • 2 XLR/TRS combo inputs with 48V phantom power
  • Class A mic preamps with up to 35 dBu adjustable gain
  • 24-bit / 96 kHz converters, 105 dB dynamic range
  • USB 2.0 bus-powered, steel chassis
  • Bundles Studio One Artist DAW

Pros and cons

Focusrite Scarlett 4i4 4th Gen

Pros

  • Two clean preamps handle dual-mic podcast setups
  • Four balanced outputs for flexible monitoring routing
  • MIDI I/O included - less common at this price
  • Independent 48V per channel (mix condensers and dynamics freely)

Cons

  • Only one headphone output
  • Larger footprint than the 2i2 - takes more desk space
  • Line inputs are rear-panel only - not ideal for live instrument switching

PreSonus AudioBox USB 96

Pros

  • Steel chassis - genuinely road-durable
  • MIDI I/O included at an entry-level price
  • Class-compliant on Mac, Windows, and iOS
  • Solid Studio One Artist software bundle

Cons

  • 96 kHz max sample rate - no 192 kHz recording
  • Preamps have less gain than newer designs
  • USB-A only - older connector standard

The verdict

Choose Focusrite Scarlett 4i4 4th Gen if

Producers or podcasters who need two clean mic preamps, room for outboard gear, and MIDI connectivity in one box.

The 4i4 is where the Scarlett line starts making sense for more complex setups. Two XLR preamps handle a host and a guest simultaneously, the four balanced outputs let you route to two separate monitor pairs or an external headphone…

Read the full Focusrite Scarlett 4i4 4th Gen review →

Choose PreSonus AudioBox USB 96 if

Beginners or mobile podcasters who want a durable, no-fuss two-input interface with MIDI and a solid DAW bundle.

The AudioBox USB 96 has outlasted almost every competitor at its price point by simply being reliable. The steel chassis survives bag throws that would crack plastic units, the preamps are clean if unexciting, and MIDI I/O is a bonus…

Read the full PreSonus AudioBox USB 96 review →

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